Catenin, alpha-1 (CTNNA1) (1G5), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Catenin, alpha-1 (CTNNA1) (1G5), CF405S conjugate, 0.1mg/mL

9

Western Blot

Research Use Only

Monoclonal

1G5

0.1 mg/ml

Other Conjugate

CTNNA1

catenin alpha 1

alpha-E-catenin; CAP102; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha-1; epididymis secretory sperm binding protein; MDPT2; renal carcinoma antigen NY-REN-13

Mouse

IgG1

Catenin alpha-1

Alpha-E-catenin (also known as Alpha-1 catenin) is part of the catenin family, a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-E-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-E-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-E-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203