Catestatin [142211-96-9]

TargetMol Chemicals

Catestatin [142211-96-9]

16

142211-96-9

Chemical

Research Use Only

Catestatin

C107H173N37O26S

2425.84

Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.

3 years

C(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CO)=O)CCSC)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)CCCNC(=N)N)=O)(=O)N4[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)=O)CCC4

-20°C

12352200