Cathepsin B antibody [6C15]
GTX53252
Overview
- SupplierGeneTex
- Product NameCathepsin B antibody [6C15]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6C15
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID13030
- Target nameCtsb
- Target descriptioncathepsin B
- Target synonymscathepsin B; cathepsin B1; CB
- HostRat
- IsotypeIgG1
- Protein IDP10605
- Protein NameCathepsin B
- Scientific DescriptionThis gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203