Cathepsin B Polyclonal Antibody
RD77348A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCTSB
Overview
- SupplierReddot Biotech
- Product NameCathepsin B Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID1508
- Target nameCTSB
- Target descriptioncathepsin B
- Target synonymsamyloid precursor protein secretase; APP secretase; APPS; cathepsin B; cathepsin B1; CPSB; cysteine protease; epididymis secretory sperm binding protein; RECEUP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203