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Cathepsin L antibody [RM0166-5G14]

Research Use Only
GTX53257
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse
TargetCtsl
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Cathepsin L antibody [RM0166-5G14]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody detects human Cathepsin L. It also cross-reacts to the pro and active forms of mouse Cathepsin H in western blotting and direct ELISA.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM0166-5G14
  • Concentration
    500 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID13039
  • Target name
    Ctsl
  • Target description
    cathepsin L
  • Target synonyms
    1190035F06Rik; Cat L; cathepsin L1; CatL; Ctsl1; fs; major excreted protein; ME; MEP; nkt; p39 cysteine proteinase; procathepsin L
  • Host
    Rat
  • Isotype
    IgG2
  • Scientific Description
    This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203