Cathepsin L antibody [RM0166-5G14]
GTX53257
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse
TargetCtsl
Overview
- SupplierGeneTex
- Product NameCathepsin L antibody [RM0166-5G14]
- Delivery Days Customer9
- Antibody SpecificityThis antibody detects human Cathepsin L. It also cross-reacts to the pro and active forms of mouse Cathepsin H in western blotting and direct ELISA.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM0166-5G14
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID13039
- Target nameCtsl
- Target descriptioncathepsin L
- Target synonyms1190035F06Rik; Cat L; cathepsin L1; CatL; Ctsl1; fs; major excreted protein; ME; MEP; nkt; p39 cysteine proteinase; procathepsin L
- HostRat
- IsotypeIgG2
- Scientific DescriptionThis gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015]
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203