Cathepsin L antibody [RM0166-5G14]

GeneTex

Cathepsin L antibody [RM0166-5G14]

9

This antibody detects human Cathepsin L. It also cross-reacts to the pro and active forms of mouse Cathepsin H in western blotting and direct ELISA.

WB: 1:500 - 1:1000. IHC-P: 1:200 - 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

RM0166-5G14

500 ug/ml

Unconjugated

Ctsl

cathepsin L

1190035F06Rik; Cat L; cathepsin L1; CatL; Ctsl1; fs; major excreted protein; ME; MEP; nkt; p39 cysteine proteinase; procathepsin L

Rat

IgG2

Cathepsin L1

This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015]

Mouse

-20°C or -80°C,2°C to 8°C

12352203