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WB analysis of HeLa cells treated with etoposide 25uM (1h) lysate using GTX86946 Cathepsin L (cleaved Thr288) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of HeLa cells treated with etoposide 25uM (1h) lysate using GTX86946 Cathepsin L (cleaved Thr288) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of HeLa cells treated with etoposide 25uM (1h) lysate using GTX86946 Cathepsin L (cleaved Thr288) antibody. The lane on the right is blocked with the synthesized peptide.

Cathepsin L (cleaved Thr288) antibody

Research Use Only
GTX86946
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCTSL
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Cathepsin L (cleaved Thr288) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Cathepsin L (cleaved Thr288) antibody detects endogenous levels of fragment of activated CATL1 resulting from cleavage adjacent to Thr288.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1514
  • Target name
    CTSL
  • Target description
    cathepsin L
  • Target synonyms
    cathepsin L1; CATL; CTSL1; major excreted protein; MEP; procathepsin L
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203