Caulophylline (N-Methylcytisine) [486-86-2]
S3298
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameCaulophylline (N-Methylcytisine) [486-86-2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionCaulophylline (N-Methylcytisine, Caulophyllin, NMC) is a tricyclic quinolizidine alkaloid with anti-inflammatory activities. Caulophylline binds to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia with Kd of 50 nM. Caulophylline significantly reduces myeloperoxidase (MPO) activity, blocks the activation of NF-kappaB by inhibiting IkappaB and IKK phosphorylation.
- UNSPSC12352200