CAV1 Polyclonal Antibody
RD76696A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAV1
Overview
- SupplierReddot Biotech
- Product NameCAV1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID857
- Target nameCAV1
- Target descriptioncaveolin 1
- Target synonymsBSCL3; caveolin 1, caveolae protein, 22kDa; caveolin-1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; PPH3; VIP21
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203