Bio-Connect

Cav1.2 Polyclonal Antibody

Research Use Only
RD76741A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCACNA1C
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    Cav1.2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.6 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID775
  • Target name
    CACNA1C
  • Target description
    calcium voltage-gated channel subunit alpha1 C
  • Target synonyms
    CACH2; CACN2; CACNL1A1; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; CaV1.2; CCHL1A1; DHPR, alpha-1 subunit; LQT8; TS; TS. LQT8; voltage-dependent L-type Ca2+ channel alpha 1 subunit; voltage-dependent L-type calcium channel subunit alpha-1C; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203