Caveolin 1 antibody

GeneTex

Caveolin 1 antibody

9

WB: 1-2 microg/ml. ICC/IF: 1-2 microg/ml. FACS: 3-5 microg/106 cells. IP: 5 microg. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CAV1

caveolin 1

caveolin-1; vesicular integral-membrane protein VIP21

Rabbit

IgG

Caveolin-1

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

Canine, Hamster, Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203