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ProductsBack/Caveolin 3 antibody [N1N2], N-term

Caveolin 3 antibody [N1N2], N-term

GTX109650
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAV3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Caveolin 3 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:20000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID859
  • Target name
    CAV3
  • Target description
    caveolin 3
  • Target synonyms
    caveolin-3; cavolin 3; LGMD1C; LQT9; M-caveolin; MPDT; RMD2; VIP21; VIP-21
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP56539
  • Protein Name
    Caveolin-3
  • Scientific Description
    This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Adult-onset autosomal dominant centronuclear myopathy due to BIN1 mutations. Boehm J et al., 2014 Dec, Brain
    Read more
  • Alterations of excitation-contraction coupling and excitation coupled Ca(2+) entry in human myotubes carrying CAV3 mutations linked to rippling muscle. Ullrich ND et al., 2011 Mar, Hum Mutat
    Read more