Cbl-b-IN-2

TargetMol Chemicals

Cbl-b-IN-2

114

2503325-21-9

Chemical

Cbl-b-IN-2

C29H30F5N5O2

575.57

Cbl-b-IN-2 is an orally active biological compound that inhibits the E3 enzyme Casitas b lineage lymphoma proto-oncogene b (Cbl-b) in the ubiquitin proteasome pathway and can be used in the study of diseases that modulate the immune system and are susceptible to regulation by the immune system. Cbl-b-IN-2 can also be used in cancer research alone or in combination with one or more immune checkpoint inhibitors, antitumour agents and radiopharmaceuticals.

3 years

C(C1(COC1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC(CN5C[C@@H](C)C(F)(F)CC5)=CC4C(F)(F)F)C=6N(C)C=NN6

-20°

12352200