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CBT-295

Research Use Only
HY-169004
MedChem Express
Estimated Purity99.34
Product group Chemicals
Molecular Weight329.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CBT-295
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    99.34
  • Molecular Formula
    C18H20ClN3O
  • Molecular Weight
    329.82
  • Scientific Description
    CBT-295 is an orally active autotaxin (ATX) inhibitor. CBT-295 exhibits a significant reduction in inflammatory cytokines like TGF-beta, TNF-alpha and IL-6 levels, also reduced bile duct proliferation marker CK-19 and lowered liver fibrosis. The reversal of liver fibrosis with CBT-295 led to a reduction in blood and brain ammonia levels. CBT-295 also reduced neuroinflammation induced by ammonia. CBT-295 is promising for research of liver cirrhosis and associated encephalopathy[1].
  • SMILES
    O=C1C=C(C)N(CCCCC)C2=NC(C3=CC=C(Cl)C=C3)=CN12
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200