Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA004600ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA004600ESR2HU at dilution of 1:100
CBX4 Antibody
CSB-PA004600ESR2HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCBX4
Overview
- SupplierCusabio
- Product NameCBX4 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8535
- Target nameCBX4
- Target descriptionchromobox 4
- Target synonymschromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; polycomb 2 homolog
- HostRabbit
- IsotypeIgG
- Protein IDO00257
- Protein NameE3 SUMO-protein ligase CBX4
- Scientific DescriptionE3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \\\Lys-119\\\, rendering chromatin heritably changed in its expressibility.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203