CBX5 Monoclonal Antibody

Elabscience

CBX5 Monoclonal Antibody

12

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

Clone:7B6

1 mg/ml

Unconjugated

CBX5

chromobox 5

HEL25, HP1, HP1A, HP1alpha, chromobox protein homolog 5, HP1 alpha homolog, HP1-ALPHA, HP1Hs alpha, antigen p25, chromobox homolog 5 (HP1 alpha homolog, Drosophila), epididymis luminal protein 25, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha

Mouse

IgG

Chromobox protein homolog 5

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

-20°C

41116161