CBX5 Monoclonal Antibody

Reddot Biotech

CBX5 Monoclonal Antibody

5

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

Clone:7B6

1 mg/ml

Unconjugated

CBX5

chromobox 5

antigen p25; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HP1; HP1 alpha homolog; HP1A; HP1-ALPHA; HP1Hs alpha

Mouse

IgG

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Human, Mouse, Rat

-20°C

12352203