CCF642

AbMole BioScience

CCF642

9

346640-08-2

Chemical

Research Use Only

C15H10N2O4S3

378.45

CCF642 is a cell-permeable protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action that most likely involves PDI active-site CGHCK motifs instead of cysteine known to be targeted by PACMA 31.

COC1=CC=C(C=C1)N2C(=S)S\C(=C/C3=CC=C(S3)[N+]([O-])=O)C2=O

12352200