CCL4 Antibody

Cusabio

CCL4 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

CCL4

C-C motif chemokine ligand 4

ACT2; AT744.1; C-C motif chemokine 4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; LAG1; LAG-1; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta(1-69); PAT 744; SCYA2; SCYA4; secreted protein G-26; SIS-gamma; small inducible cytokine A4 (homologous to mouse Mip-1b); T-cell activation protein 2

Rabbit

IgG

C-C motif chemokine 4

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Human

-20°C or -80°C

12352203