CCT241736 [1402709-93-6]
HY-18161
CAS Number1402709-93-6
Product group Chemicals
Estimated Purity99.88
Molecular Weight456.37
Overview
- SupplierMedChem Express
- Product NameCCT241736 [1402709-93-6]
- Delivery Days Customer10
- CAS Number1402709-93-6
- CertificationResearch Use Only
- Estimated Purity99.88
- Molecular FormulaC22H23Cl2N7
- Molecular Weight456.37
- Scientific DescriptionCCT241736 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).
- SMILESCC1=NN(C)C=C1C2=NC3=C(N4CCN(CC5=CC=C(Cl)C=C5)CC4)C(Cl)=CN=C3N2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200