CD11b antibody [OX-42] (PE)
GTX76061
Overview
- SupplierGeneTex
- Product NameCD11b antibody [OX-42] (PE)
- Delivery Days Customer9
- Application Supplier NoteOptimal dilutions/concentrations should be determined by the researcher.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX-42
- Concentration0.1 mg/ml
- ConjugateRPE
- Gene ID25021
- Target nameItgam
- Target descriptionintegrin subunit alpha M
- Target synonymsCd11b; integrin alpha-M; integrin, alpha M
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionRecognises most macrophages (including resident peritoneal and activated macrophages), Kupffer cells, but only about 35% alveolar macrophages. The MRC OX-42 antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. MRC OX-42 precipitates three polypeptides of M.W 160,000, 103,000 and 95,000. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for iC3b called CR3.
- ReactivityRat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
References
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- Pro-Inflammatory Effect of Gliadins and Glutenins Extracted from Different Wheat Cultivars on an In Vitro 3D Intestinal Epithelium Model. Truzzi F et al., 2020 Dec 26, Int J Mol SciRead more
- Investigating The Alterations of Oxidative Stress Status, Antioxidant Defense Mechanisms, MAP Kinase and Mitochondrial Apoptotic Pathway in Adipose-Derived Mesenchymal Stem Cells from STZ Diabetic Rats. Aminzadeh A et al., 2020 Jul, Cell JRead more
- G-protein-coupled estrogen receptor activation upregulates interleukin-1 receptor antagonist in the hippocampus after global cerebral ischemia: implications for neuronal self-defense. Bai N et al., 2020 Feb 1, J NeuroinflammationRead more
- Microglia-Derived Adiposomes are Potential Targets for the Treatment of Ischemic Stroke. Lin CH et al., 2019 Jul, Cell Mol NeurobiolRead more
- The P2X7 Receptor, Cathepsin S and Fractalkine in the Trigeminal Subnucleus Caudalis Signal Persistent Hypernociception in Temporomandibular Rat Joints. Bonfante R et al., 2018 Nov 1, NeuroscienceRead more
- Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. Lin CH et al., 2016, PLoS OneRead more
- Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury. Nakajima H et al., 2012 May 20, J NeurotraumaRead more
- IL-1beta in the trigeminal subnucleus caudalis contributes to extra-territorial allodynia/hyperalgesia following a trigeminal nerve injury. Takahashi K et al., 2011 May, Eur J PainRead more
- Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes. Zhao Z et al., 2009 Feb, Glycoconj JRead more