
Staining of rat peritoneal macrophages using CD11b: FITC antibody (GTX21212) and FITC mouse IgG2a isotype control
CD11b/c equivalent antibody [OX 42] (FITC)
GTX21212
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityRat
TargetItgam
Overview
- SupplierGeneTex
- Product NameCD11b/c equivalent antibody [OX 42] (FITC)
- Delivery Days Customer9
- Antibody SpecificityRecognises a common epitope shared by CD11b/c and precipitates three polypeptides of Mw160kD, 103kD and 95kD; a fainter band may also be seen at 133kD. It reacts with all macrophages in the peritoneal cavity, activated macrophages and Kupffer cells, but w
- Application Supplier NoteFACS: Use at a dilution of 1/1 - 1/20 (10microl/10^6cells). IHC-P: Use at a dilution of 1/1 - 1/20. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX 42
- Concentration0.1 mg/ml
- ConjugateFITC
- Gene ID25021
- Target nameItgam
- Target descriptionintegrin subunit alpha M
- Target synonymsCd11b; integrin alpha-M; integrin, alpha M
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThe principal use of this antibody is in the study of functional heterogeneity of macrophages; it may be used to follow macrophage differentiation and to investigate the function of the CD11b/c equivalent antigen.
- ReactivityRat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
References
- Acupuncture attenuates the development of diabetic peripheral neuralgia by regulating P2X4 expression and inflammation in rat spinal microglia. Tang HY et al., 2020 Sep 23, J Physiol SciRead more
- The P2X7 Receptor, Cathepsin S and Fractalkine in the Trigeminal Subnucleus Caudalis Signal Persistent Hypernociception in Temporomandibular Rat Joints. Bonfante R et al., 2018 Nov 1, NeuroscienceRead more
- Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury. Nakajima H et al., 2012 May 20, J NeurotraumaRead more