Western Blot Positive WB detected in A375 whole cell lysate All lanes CD146 antibody at 0.6microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 72 KDa Observed band size: 120 KDa
Western Blot Positive WB detected in A375 whole cell lysate All lanes CD146 antibody at 0.6microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 72 KDa Observed band size: 120 KDa
CD146 Recombinant Monoclonal Antibody
CSB-RA013563A0HU
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMCAM
Overview
- SupplierCusabio
- Product NameCD146 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID8A10
- ConjugateUnconjugated
- Gene ID4162
- Target nameMCAM
- Target descriptionmelanoma cell adhesion molecule
- Target synonymsCD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MelCAM; METCAM; MUC18; S-endo 1 endothelial-associated antigen
- IsotypeIgG
- Protein IDP43121
- Protein NameCell surface glycoprotein MUC18
- Scientific DescriptionPlays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203