CD15 Antibody / SSEA-1

Biorbyt

CD15 Antibody / SSEA-1

16

Optimal dilution of the recombinant CD15 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT FACS, IF, IHC-P

Research Use Only

Monoclonal

FUT4/1478R

Unconjugated

FUT4

fucosyltransferase 4

alpha (1,3) fucosyltransferase, myeloid-specific; alpha-(1,3)-fucosyltransferase 4; CD15; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; ELFT; FCT3A; fucosyltransferase IV; FUC-TIV; fucT-IV; FUTIV; galactoside 3-L-fucosyltransferase; Lewis X; LeX; SSEA-1; stage-specific embryonic antigen 1

Rabbit

IgG

Alpha-(1,3)-fucosyltransferase 4

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on > 95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203