Bio-Connect

CD177 Polyclonal Antibody

RD81512A
Reddot Biotech
TargetCD177
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CD177 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID57126
  • Target name
    CD177
  • Target description
    CD177 molecule
  • Target synonyms
    CD177 antigen; cell surface receptor; HNA2A; HNA-2a; human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; polycythemia rubra vera protein 1; PRV1; PRV-1
  • Scientific Description
    This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegeners granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203