CD20 antibody [2H7]
GTX00466
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Primate
TargetMS4A1
Overview
- SupplierGeneTex
- Product NameCD20 antibody [2H7]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2H7
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID931
- Target nameMS4A1
- Target descriptionmembrane spanning 4-domains A1
- Target synonymsB1; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CVID5; FMC7; LEU-16; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1; S7
- HostMouse
- IsotypeIgG2b
- Protein IDP11836
- Protein NameB-lymphocyte antigen CD20
- Scientific DescriptionThis gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Fibroblast growth factor receptor 3 (FGFR3) associated with the CD20 antigen regulates the rituximab-induced proliferation inhibition in B-cell lymphoma cells. Kotani N et al., 2012 Oct 26, J Biol ChemRead more