![CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1952), CF640R conjugate, 0.1mg/mL [26628-22-8] CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1952), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-355.jpeg)
CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1952), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC401952
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCR2
Overview
- SupplierBiotium
- Product NameCD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1952), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCR2/1952
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID1380
- Target nameCR2
- Target descriptioncomplement C3d receptor 2
- Target synonymsC3DR; CD21; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor type 2; CR; CVID7; EBV receptor; SLEB9
- HostMouse
- IsotypeIgG1
- Protein IDP20023
- Protein NameComplement receptor type 2
- Scientific DescriptionThis antibody recognizes a protein of 140 kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203