Bio-Connect

CD22(Myg13), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040974
Biotium
ApplicationsFunctional Assay, Flow Cytometry, Western Blot
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetCD22
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Overview

  • Supplier
    Biotium
  • Product Name
    CD22(Myg13), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Myg13
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID933
  • Target name
    CD22
  • Target description
    CD22 molecule
  • Target synonyms
    B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP20273
  • Protein Name
    B-cell receptor CD22
  • Scientific Description
    This antibody ecognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203