CD22(Myg13), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040974
ApplicationsFunctional Assay, Flow Cytometry, Western Blot
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetCD22
Overview
- SupplierBiotium
- Product NameCD22(Myg13), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMyg13
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID933
- Target nameCD22
- Target descriptionCD22 molecule
- Target synonymsB-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
- HostMouse
- IsotypeIgG1
- Protein IDP20273
- Protein NameB-cell receptor CD22
- Scientific DescriptionThis antibody ecognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203