Bio-Connect

CD257 / BAFF / TNFSF13B (C257/1638), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401638
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetTNFSF13B
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Overview

  • Supplier
    Biotium
  • Product Name
    CD257 / BAFF / TNFSF13B (C257/1638), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    C257/1638
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID10673
  • Target name
    TNFSF13B
  • Target description
    TNF superfamily member 13b
  • Target synonyms
    ApoL related ligand TALL-1; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; epididymis secretory sperm binding protein; TALL1; TALL-1; THANK; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; ZTNF4
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ9Y275
  • Protein Name
    Tumor necrosis factor ligand superfamily member 13B
  • Scientific Description
    BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203