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CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), CF640R conjugate, 0.1mg/mL [26628-22-8]

CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC402366
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetTNFRSF17
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Overview

  • Supplier
    Biotium
  • Product Name
    CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BCMA/2366
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID608
  • Target name
    TNFRSF17
  • Target description
    TNF receptor superfamily member 17
  • Target synonyms
    B cell maturation antigen; B-cell maturation factor; B-cell maturation protein; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ02223
  • Protein Name
    Tumor necrosis factor receptor superfamily member 17
  • Scientific Description
    The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203