CD28 Antibody (clone ANC28.1/5D10, RPE)

LifeSpan BioSciences

CD28 Antibody (clone ANC28.1/5D10, RPE)

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CD28 expressed on T cells and also on BHK cells transfected with human CD28. This antibody has been characterized as a superagonist.

Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.. ELISA, Flo, Func Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. WB

Functional Assay, Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC28.1/5D10

RPE

...

CD28

CD28 molecule

T-cell-specific surface glycoprotein CD28; Tp44

Mouse

IgG1

Human

2°C to 8°C

12352203