CD28 antibody [YTH913.12]
GTX42128
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetCD28
Overview
- SupplierGeneTex
- Product NameCD28 antibody [YTH913.12]
- Delivery Days Customer9
- Application Supplier NoteFACS: 1/25-1/50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDYTH913.12
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID940
- Target nameCD28
- Target descriptionCD28 molecule
- Target synonymsT-cell-specific surface glycoprotein CD28; Tp44
- HostRat
- IsotypeIgG2b
- Protein IDP10747
- Protein NameT-cell-specific surface glycoprotein CD28
- Scientific DescriptionThe protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Association of Pathogenic Th17 Cells with the Disease Severity and Its Potential Implication for Biological Treatment Selection in Psoriasis Patients. Aguilar-Flores C et al., 2020, Mediators InflammRead more
- The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages. Svensson-Arvelund J et al., 2015 Feb 15, J ImmunolRead more
- Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells. Litjens NH et al., 2012 Feb 1, J ImmunolRead more
- Regulation of IL-17 in chronic inflammation in the human lung. Pridgeon C et al., 2011 Jun, Clin Sci (Lond)Read more
- Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol. Mjoesberg J et al., 2009 Jul 1, J ImmunolRead more
- Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy. Kropf P et al., 2007 Apr, Eur J ImmunolRead more
- High rate of mutation reporter gene inactivation during human T cell proliferation. Gabdoulkhakova A et al., 2007 Feb, ImmunogeneticsRead more
- Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease. Verkade MA et al., 2007 Jan, Nephrol Dial TransplantRead more
- CD28 is not directly involved in the response of human CD3- CD56+ natural killer cells to lipopolysaccharide: a role for T cells. Goodier MR et al., 2004 Apr, ImmunologyRead more
- Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire. Battaglia A et al., 2003 Nov, ImmunologyRead more