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ProductsBack/CD28 antibody [YTH913.12] (Low endotoxin, azide free)

CD28 antibody [YTH913.12] (Low endotoxin, azide free)

GTX42131
GeneTex
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Other Application
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCD28
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD28 antibody [YTH913.12] (Low endotoxin, azide free)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Functional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    YTH913.12
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID940
  • Target name
    CD28
  • Target description
    CD28 molecule
  • Target synonyms
    T-cell-specific surface glycoprotein CD28; Tp44
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDP10747
  • Protein Name
    T-cell-specific surface glycoprotein CD28
  • Scientific Description
    The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Association of Pathogenic Th17 Cells with the Disease Severity and Its Potential Implication for Biological Treatment Selection in Psoriasis Patients. Aguilar-Flores C et al., 2020, Mediators Inflamm
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  • The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages. Svensson-Arvelund J et al., 2015 Feb 15, J Immunol
    Read more
  • Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells. Litjens NH et al., 2012 Feb 1, J Immunol
    Read more
  • Regulation of IL-17 in chronic inflammation in the human lung. Pridgeon C et al., 2011 Jun, Clin Sci (Lond)
    Read more
  • Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol. Mjoesberg J et al., 2009 Jul 1, J Immunol
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  • Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy. Kropf P et al., 2007 Apr, Eur J Immunol
    Read more
  • High rate of mutation reporter gene inactivation during human T cell proliferation. Gabdoulkhakova A et al., 2007 Feb, Immunogenetics
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  • Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease. Verkade MA et al., 2007 Jan, Nephrol Dial Transplant
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  • CD28 is not directly involved in the response of human CD3- CD56+ natural killer cells to lipopolysaccharide: a role for T cells. Goodier MR et al., 2004 Apr, Immunology
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  • Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire. Battaglia A et al., 2003 Nov, Immunology
    Read more