CD28, Canine (HEK293, mFc)

MedChem Express

CD28, Canine (HEK293, mFc)

10

Research Use Only

95.0

CD28 Protein plays a pivotal role in T-cell activation, promoting cell proliferation, cytokine production, and T-cell survival. Upon ligation with TCR/CD3 and CD40L costimulation, CD28 enhances the production of IL4 and IL10 in T-cells, contributing to immune response modulation. Additionally, isoform 3 of CD28 facilitates CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. The protein forms homodimers through disulfide linkages and interacts with various molecules. CD28 Protein, Canine (HEK293, mFc) is the recombinant canine-derived CD28 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CD28 Protein, Canine (HEK293, mFc) is 136 a.a., with molecular weight of 50-70 kDa.

-20°C

12352202