CD3 antibody [CD3-12] (FITC)
GTX43629
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityAmphibian, Avian, Bovine, Canine, Chicken, Equine, Feline, Human, Mammals, Monkey, Mouse, Porcine, Primate, Rabbit, Xenopus
TargetCD3E
Overview
- SupplierGeneTex
- Product NameCD3 antibody [CD3-12] (FITC)
- Delivery Days Customer9
- Antibody SpecificityThis antibody raised against a peptide representing an invariant cytoplasmic sequence within the CD3ε chain recognizes human CD3ε.
- Application Supplier NoteFACS: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCD3-12
- Concentration0.1 mg/ml
- ConjugateFITC
- FormulationLiquid
- Gene ID916
- Target nameCD3E
- Target descriptionCD3e molecule
- Target synonymsCD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; IMD18; T3E; T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; TCRE
- HostRat
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- ReactivityAmphibian, Avian, Bovine, Canine, Chicken, Equine, Feline, Human, Mammals, Monkey, Mouse, Porcine, Primate, Rabbit, Xenopus
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
References
- Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens. Zhang L et al., 2018 Oct, Mol Cell ProbesRead more
- Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine. Sun F et al., 2016, PLoS OneRead more