CD3 antibody [OKT3]
GTX79906
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Primate
TargetCD3D
Overview
- SupplierGeneTex
- Product NameCD3 antibody [OKT3]
- Delivery Days Customer9
- Antibody SpecificityThis antibody recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogen
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOKT3
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID915
- Target nameCD3D
- Target descriptionCD3d molecule
- Target synonymsCD3 antigen, delta subunit; CD3 delta; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; IMD19; OKT3, delta chain; T3D; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain
- HostMouse
- IsotypeIgG2a
- Protein IDP04234
- Protein NameT-cell surface glycoprotein CD3 delta chain
- ReactivityHuman, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Histological tumor response to neoadjuvant chemotherapy correlates to Immunoscore in colorectal cancer liver metastases patients. Zhang C et al., 2021 Dec, J Surg OncolRead more
- Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation. Sanchez-Villanueva JA et al., 2019, PLoS OneRead more
- STAT5B: A Differential Regulator of the Life and Death of CD4(+) Effector Memory T Cells. Majri SS et al., 2018 Jan 1, J ImmunolRead more
- Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity. Haga-Friedman A et al., 2012 Jun 1, J ImmunolRead more
- IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in CD4 T cells lacking the IL-7Ralpha. Bikker A et al., 2012 Jun, Rheumatology (Oxford)Read more
- A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease. Bagnara D et al., 2011 May 19, BloodRead more
- A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Nguyen V et al., 2009 Nov, Mol Cell ProteomicsRead more
- The quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a function of the anti-CD3 antibody isotype. Bibollet-Ruche F et al., 2008 Oct, J VirolRead more
- CD1a and CD1c activate intrathyroidal T cells during Graves disease and Hashimotos thyroiditis. Roura-Mir C et al., 2005 Mar 15, J ImmunolRead more
- The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. Sato Y et al., 1986 Dec, Am J PatholRead more