CD3 epsilon antibody [MEM-92] (Low Endotoxin)

GeneTex

CD3 epsilon antibody [MEM-92] (Low Endotoxin)

9

Functional Assay, Flow Cytometry, ImmunoPrecipitation

Research Use Only

Monoclonal

MEM-92

1 mg/ml

Unconjugated

CD3E

CD3 epsilon subunit of T-cell receptor complex

CD3epsilon, IMD18, T3E, TCRE, T-cell surface glycoprotein CD3 epsilon chain, CD3-epsilon, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain

Mouse

IgM

T-cell surface glycoprotein CD3 epsilon chain

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

2°C to 8°C

12352203