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CD33 Antibody, FITC conjugated

Research Use Only
CSB-PA004925LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetCD33
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Overview

  • Supplier
    Cusabio
  • Product Name
    CD33 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Formulation
    Liquid
  • Gene ID945
  • Target name
    CD33
  • Target description
    CD33 molecule
  • Target synonyms
    CD33 antigen (gp67); CD33 molecule transcript; gp67; myeloid cell surface antigen CD33; p67; sialic acid-binding Ig-like lectin 3; SIGLEC3; SIGLEC-3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP20138
  • Protein Name
    Myeloid cell surface antigen CD33
  • Scientific Description
    Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203