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ProductsBack/CD33 antibody

CD33 antibody

Research Use Only
ORB67209
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCD33
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Overview

  • Supplier
    Biorbyt
  • Product Name
    CD33 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:500-1:1000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID945
  • Target name
    CD33
  • Target description
    CD33 molecule
  • Target synonyms
    CD33 antigen (gp67); CD33 molecule transcript; gp67; myeloid cell surface antigen CD33; p67; sialic acid-binding Ig-like lectin 3; SIGLEC3; SIGLEC-3
  • Host
    Rabbit
  • Protein IDP20138
  • Protein Name
    Myeloid cell surface antigen CD33
  • Scientific Description
    Rabbit polyclonal to CD33.Myeloid cell surface antigen CD33 belongs to the immunoglobulin superfamily. It is a putativeadhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding tocells. It preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may bemasked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruitingcytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction throughdephosphorylation of signaling molecules. It induces apoptosis in acute myeloid leukemia.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203