CD34 Monoclonal Antibody,PE Conjugated

Cusabio

CD34 Monoclonal Antibody,PE Conjugated

20

Flow Cytometry, ImmunoFluorescence, ELISA

Research Use Only

Monoclonal

RPE, Unconjugated

CD34

CD34 molecule

CD34 antigen; hematopoietic progenitor cell antigen CD34

Mouse

IgG3

Hematopoietic progenitor cell antigen CD34

D34 reacts with CD34 molecule, a 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 43A1 belongs to the class II epitope. * CD34 mAb is useful for detection and saparation of hematopoietic stem cells.1. Schlossman, SL et al., eds. (1995) Leucocyte Typing V : White Cell Differentiation Antigens, Oxford University Press, New York.2. Freeman SD et al., (1995) Blood 85:20053. Thomas R and Lipsky PE. (1994) J Immunol 153:40164. Nakamura Y. et al., (1994) Blood 83:1442

Human

-20°C or -80°C

12352203