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CD36 antibody [C1C3]

GTX100642
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCD36
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD36 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.47 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID948
  • Target name
    CD36
  • Target description
    CD36 molecule (CD36 blood group)
  • Target synonyms
    BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, platelet glycoprotein 4, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule (CD36 blood group) transcript, CD36 molecule (thrombospondin receptor), GPIIIB, PAS IV, PAS-4 protein, cluster determinant 36, fatty acid translocase, glycoprotein IIIb, leukocyte differentiation antigen CD36, platelet glycoprotein IV, scavenger receptor class B, member 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP16671
  • Protein Name
    Platelet glycoprotein 4
  • Scientific Description
    The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Rodriguez-Lopez C, Santalla A, Valenzuela PL, et al. Muscle glycogen unavailability and fat oxidation rate during exercise: Insights from McArdle disease. J Physiol. 2023,601(3):551-566. doi: 10.1113/JP283743
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  • Sui D, Yu H. Protective roles of apremilast via Sirtuin 1 in atherosclerosis. Bioengineered. 2022,13(5):13872-13881. doi: 10.1080/21655979.2022.2085390
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  • Ageeli W, Zhang X, Ogbonnaya CN, et al. Multimodality Characterization of Cancer-Associated Fibroblasts in Tumor Microenvironment and Its Correlation With Ultrasound Shear Wave-Measured Tissue Stiffness in Localized Prostate Cancer. Front Oncol. 2022,12:822476. doi: 10.3389/fonc.2022.822476
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  • Njau F, Haller H. Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis. Antioxidants (Basel). 2021,10(11). doi: 10.3390/antiox10111798
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  • Brusini R, Dormont F, Cailleau C, et al. Squalene-based nanoparticles for the targeting of atherosclerotic lesions. Int J Pharm. 2020,581:119282. doi: 10.1016/j.ijpharm.2020.119282
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  • Tsai YT, Ruan JW, Chang CS, et al. Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Nutrients. 2020,12(3). doi: 10.3390/nu12030726
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  • Tsukahara T. 1-O-alkyl glycerophosphate-induced CD36 expression drives oxidative stress in microglial cells. Cell Signal. 2020,65:109459. doi: 10.1016/j.cellsig.2019.109459
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  • Xu M, Xue RQ, Lu Y, et al. Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway. Cardiovasc Res. 2019,115(3):530-545. doi: 10.1093/cvr/cvy217
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  • Sun Q, Zhang W, Wang L, et al. Hypermethylated CD36 gene affected the progression of lung cancer. Gene. 2018,678:395-406. doi: 10.1016/j.gene.2018.06.101
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