Surface staining of PHA stimulated human peripheral blood lymphocytes with anti-human CD38 (HIT2) PE.
Surface staining of PHA stimulated human peripheral blood lymphocytes with anti-human CD38 (HIT2) PE.
CD38 antibody [HIT2] (PerCP)
GTX80119
Overview
- SupplierGeneTex
- Product NameCD38 antibody [HIT2] (PerCP)
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHIT2
- ConjugatePerCP
- Gene ID952
- Target nameCD38
- Target descriptionCD38 molecule
- Target synonyms2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; CD38 antigen (p45); cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203