![CD40, Mouse(FGK45.5), CF405S conjugate, 0.1mg/mL [26628-22-8] CD40, Mouse(FGK45.5), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2016/12/placeholder.png)
CD40, Mouse(FGK45.5), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC042005
ApplicationsFunctional Assay, Flow Cytometry
Product group Antibodies
ReactivityBovine, Mouse, Rat
TargetCd40
Overview
- SupplierBiotium
- Product NameCD40, Mouse(FGK45.5), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDFGK45.5
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID21939
- Target nameCd40
- Target descriptionCD40 antigen
- Target synonymsAI326936; B-cell surface antigen CD40; Bp5; Bp50; CD40L receptor; GP39; HIGM1; IGM; IMD3; p5; p50; T-BAM; T-cell differentiation antigen; Tnfr; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5
- HostRat
- IsotypeIgG2a
- Protein IDP27512
- Protein NameTumor necrosis factor receptor superfamily member 5
- Scientific DescriptionUpon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203