CD41 antibody [P2]

GeneTex

CD41 antibody [P2]

9

Reacts with gpIIb in the intact complex with gpIIIa, but not with IIb or IIIa, separately. Inhibits plateletaggregation induced by thrombin, collagen and ADP. The molecular weight of the recognized complex is135 kDa/95 kDa.

IHC-Fr: 1:50-1:100. FACS: 2 microg. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

P2

0.20 mg/ml

Unconjugated

ITGA2B

integrin subunit alpha 2b

alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPalpha IIb; GPIIb; GT; GT1; GTA; HPA3; integrin alpha-IIb; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93

Mouse

IgG1

Integrin alpha-IIb

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203