CD45 antibody [IH1]

GeneTex

CD45 antibody [IH1]

9

Detects all isoforms (180-220 kDa)

For IF: Use at a concentration of 5-20microg/ml. For IP: Use at a concentration of 5-20microg/ml. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

IH1

0.5 mg/ml

Unconjugated

Mouse

IgG

The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.

Human

-20°C or -80°C,2°C to 8°C

12352203