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CD50 (ICAM-3)(101-1D2), CF640R conjugate, 0.1mg/mL [26628-22-8]

CD50 (ICAM-3)(101-1D2), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC400177
Biotium
ApplicationsFunctional Assay, Flow Cytometry, ELISA
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetICAM3
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Overview

  • Supplier
    Biotium
  • Product Name
    CD50 (ICAM-3)(101-1D2), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    101-1D2
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3385
  • Target name
    ICAM3
  • Target description
    intercellular adhesion molecule 3
  • Target synonyms
    CD50; CDW50; ICAM-3; ICAM-R; intercellular adhesion molecule 3
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP32942
  • Protein Name
    Intercellular adhesion molecule 3
  • Scientific Description
    Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203