Bio-Connect

CD54 Polyclonal Antibody

RD76761A
Reddot Biotech
TargetICAM1
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CD54 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    0.3 mg/ml
  • Gene ID3383
  • Target name
    ICAM1
  • Target description
    intercellular adhesion molecule 1
  • Target synonyms
    BB2; CD54; cell surface glycoprotein P3.58; epididymis secretory sperm binding protein; ICAM-1; intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; P3.58
  • Scientific Description
    This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203