CD54 Polyclonal Antibody
RD76761A
TargetICAM1
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameCD54 Polyclonal Antibody
- Delivery Days Customer5
- Concentration0.3 mg/ml
- Gene ID3383
- Target nameICAM1
- Target descriptionintercellular adhesion molecule 1
- Target synonymsBB2; CD54; cell surface glycoprotein P3.58; epididymis secretory sperm binding protein; ICAM-1; intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; P3.58
- Scientific DescriptionThis gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
- Storage Instruction-20°C
- UNSPSC12352203