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Western Blot analysis of Huvec, hela and SKOV3 cell using CD59 Polyclonal Antibody at dilution of 1:500
Western Blot analysis of Huvec, hela and SKOV3 cell using CD59 Polyclonal Antibody at dilution of 1:500
Western Blot analysis of Huvec, hela and SKOV3 cell using CD59 Polyclonal Antibody at dilution of 1:500

CD59 Polyclonal Antibody

E-AB-13133
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    CD59 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.5mg/ml
  • Scientific Description
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
  • UNSPSC
    12352203