CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040402
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCD6
Overview
- SupplierBiotium
- Product NameCD6 (Negative Marker of T-regulatory Cells)(SPV-L14), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSPV-L14
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID923
- Target nameCD6
- Target descriptionCD6 molecule
- Target synonymsCD6 antigen; T12; T-cell differentiation antigen CD6; TP120
- HostMouse
- IsotypeIgG1
- Protein IDP30203
- Protein NameT-cell differentiation antigen CD6
- Scientific DescriptionCD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203