CD63 (Late Endosomes Marker)(NKI/C3 + LAMP3/968), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

CD63 (Late Endosomes Marker)(NKI/C3 + LAMP3/968), CF405S conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NKI/C3 LAMP3/968

0.1 mg/ml

Other Conjugate

CD63

CD63 molecule

CD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30

Mouse

IgG1

CD63 antigen

This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203