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CD7 (T-Cell Leukemia Marker)(HuLy-m2), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041252
Biotium
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCD7
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Overview

  • Supplier
    Biotium
  • Product Name
    CD7 (T-Cell Leukemia Marker)(HuLy-m2), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HuLy-m2
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID924
  • Target name
    CD7
  • Target description
    CD7 molecule
  • Target synonyms
    CD7 antigen (p41); GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP09564
  • Protein Name
    T-cell antigen CD7
  • Scientific Description
    Recognizes a protein of 40 kDa, identified as CD7 (Workshop IV; Code T165). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203